Multiscale brain functional architecture
- Introduction
- Pushing the limits of MRI
- Multiscale brain functional architecture
- Genetics and phenotypic variability in brain anatomy and function
- Brain development and plasticity
- Cognitive codes
- Translational research for neurological and psychiatric disorders
Current neuroimaging approaches in humans remain at a macroscopic scale (millions of neurons), while invasive recordings in animals explore very small ensembles of neurons. This large gap must be bridged to understand how the brain works. Interaction and synergy exist between all levels and a realistic model of the brain must take this into account. UHF MRI will allow the mesoscale to be investigated, but, considering the whole brain, huge data sets containing information on anatomy, connexions, function, metabolism… will be generated. Furthermore, comparison across individuals and across species is necessary, adding to the complexity and the size of the databases to be analysed. This program aims to produce the mathematical concepts, computer algorithms and visualization tools to explore those scales in a common frame of reference.
J.F. Mangin, C. Poupon