Scientific results
CEA
Tuesday 28 November 2006
A neuroimaging study confirms the consequences of alcohol use on the brain
A research team from the Inserm1, the CEA2 and the Paris Hospitals3 have recently demonstrated in vivo in alcohol-dependents that alcohol use leads to localised alterations in grey matter (nerve cells) and more widespread alterations in white matter (which connects all the regions of the brain). The researchers highlighted that drinking from an early age led to a reduction in grey matter volume in several regions of the brain. These findings, which came from a sample population of over 30 males, confirm the data that could previously only be obtained in post-mortem studies. The complete results were published in the journal Neuropsychopharmacology.
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A neuroimaging study confirms the consequences of alcohol use on the brain
A research team from the Inserm1, the CEA2 and the Paris Hospitals3 have recently demonstrated in vivo in alcohol-dependents that alcohol use leads to localised alterations in grey matter (nerve cells) and more widespread alterations in white matter (which connects all the regions of the brain). The researchers highlighted that drinking from an early age led to a reduction in grey matter volume in several regions of the brain. These findings, which came from a sample population of over 30 males, confirm the data that could previously only be obtained in post-mortem studies. The complete results were published in the journal Neuropsychopharmacology.
Chanraud, Martelli et al., Neuropsychopharmacology, 2006, Oct 18
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CEA
Monday 11 September 2006
Can the organisation of the infant brain explain the rapid acquisition of a first language?
Why are humans the only species that are able to master a complex language? Why is it that infants learn their first language so quickly, when adults find it so difficult to learn a second language? The answers to these questions may lie in the specific organisation of the human brain and in close collaboration among regions with different but complementary functions. These are the hypotheses advanced by the research teams at Inserm, the CEA, Paris Hospitals and the CNRS. Their work extends the conclusions drawn in 2002 by the same researchers, who demonstrated that infants activated the same brain areas as adults when they heard speech. Today their results show that the adult organisation, which presents a close collaboration between comprehension areas (the temporal area, including Wernicke’s area and verbal production areas (Broca’s area in the left lower frontal region), is already present in infants even before they learn to speak. These new findings were recently published in the online edition of the Proceedings of the National Academy of Science (PNAS).
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Can the organisation of the infant brain explain the rapid acquisition of a first language?
Why are humans the only species that are able to master a complex language? Why is it that infants learn their first language so quickly, when adults find it so difficult to learn a second language? The answers to these questions may lie in the specific organisation of the human brain and in close collaboration among regions with different but complementary functions. These are the hypotheses advanced by the research teams at Inserm, the CEA, Paris Hospitals and the CNRS. Their work extends the conclusions drawn in 2002 by the same researchers, who demonstrated that infants activated the same brain areas as adults when they heard speech. Today their results show that the adult organisation, which presents a close collaboration between comprehension areas (the temporal area, including Wernicke’s area and verbal production areas (Broca’s area in the left lower frontal region), is already present in infants even before they learn to speak. These new findings were recently published in the online edition of the Proceedings of the National Academy of Science (PNAS).
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CEA
Wednesday 21 June 2006
The astrocyte: a new therapeutic target for Huntington’s disease?
Researchers at the Frédéric Joliot Hospital Service (DRM, CEA, CNRS URA 2210 Orsay), jointly with other French and Swiss teams, have successfully characterised the mechanisms of action of ciliary neurotrophic factor (CNTF). This trophic factor is a candidate agent for the treatment of Huntington’s disease.
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The astrocyte: a new therapeutic target for Huntington’s disease?
Researchers at the Frédéric Joliot Hospital Service (DRM, CEA, CNRS URA 2210 Orsay), jointly with other French and Swiss teams, have successfully characterised the mechanisms of action of ciliary neurotrophic factor (CNTF). This trophic factor is a candidate agent for the treatment of Huntington’s disease.
Journal of Neurosciences (2006).
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Tuesday 16 May 2006
Water movements show the brain thinking
A research team at the CEA’s Frédéric Joliot Hospital Service, jointly with a team at the University of Kyoto, has recently demonstrated that neurone activation can be directly and rapidly detected by measuring the movements of water molecules in the brain. This work was published in PNAS dated 23 May 2006
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Water movements show the brain thinking
A research team at the CEA’s Frédéric Joliot Hospital Service, jointly with a team at the University of Kyoto, has recently demonstrated that neurone activation can be directly and rapidly detected by measuring the movements of water molecules in the brain. This work was published in PNAS dated 23 May 2006
PNAS (2006) 103(21): 8263-8268
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Wednesday 29 March 2006
A new potential therapeutic target for Huntington’s disease
Researchers at the Frédéric Joliot Hospital Service (DRM, CEA Orsay) jointly with others have successfully characterised a specific impairment of a mitochondrial membrane protein in Huntington’s disease.
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A new potential therapeutic target for Huntington’s disease
Researchers at the Frédéric Joliot Hospital Service (DRM, CEA Orsay) jointly with others have successfully characterised a specific impairment of a mitochondrial membrane protein in Huntington’s disease.
Mol. Biol. Cell. (2006). EOP
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Monday 13 March 2006
Capucin: a new molecular target for Huntington’s disease
The systematic search for brain molecular markers has identified a new gene that could serve to survey the onset of Huntington’s disease.
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Capucin: a new molecular target for Huntington’s disease
The systematic search for brain molecular markers has identified a new gene that could serve to survey the onset of Huntington’s disease.
Genomics (2006) 87 : 200-207
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