Research in progress at the iRCM is focused on the in vitro, ex vivo and in vivo effects of nuclear radiation and toxic substances. It includes studies in the effects of radiation and contamination from radioactive elements, on DNA lesions and repair mechanisms, and on the cellular responses to the associated diseases (cancer and non-cancer-related diseases, hereditary effects, etc.).
Orientations involve both fundamental and applied research, extending the results on the effects of radiation to stem cells and paving the way for a range of technological innovations.
The core mission of the IRCM is to deploy research programmes designed to:
analyse the fundamental mechanisms involved in DNA damage repair and cell survival,
analyse the effects of radiation on both adult and foetal somatic stem cells,
drive the research needed in order to understand how the late effects of radiation therapy are induced and appear,
analyse the mechanisms underlying the formation and transmission of the damage caused by (weak or strong doses of) ionising radiation and the consequences involved
The iRCM employs around 170 permanent research staff working in 4 departments, Genetic Instability, Repair and Recombination Research, Stems Cells and Radiation, Radiation Biology Research and Technical Innovation, and Radiation Biology and Oncology.
Orientations involve both fundamental and applied research, extending the results on the effects of radiation to stem cells and paving the way for a range of technological innovations. CEA/CNRS, CEA/Inserm, CEA/INRA and CEA/University joint research units are involved in each department in a drive to promote the Institute nationally.