Version française

NeuroSpin - Using images to undestand the brain


Understanding the human brain, its workings, its development and its dysfunctions is one of the major challenges of the 21st century. Neuro-imaging is today a crucial instrumental and conceptual tool in this quest. Its non-invasive technology provides information in vivo and in situ on brain physiology and function.


RESEARCH PROGRAMMES IN HEALTHCARE
AND SOCIAL INTERACTION
A greater understanding of human brain function will have a strong impact in several areas:
Health
Every year a growing fraction of the developed
world's population is affected by a neurological or psychiatric illness.
Ageing, restorative therapy.
Society
Interpersonal communication, education, ergonomics, art, etc.
Their aim is to:
MAP BRAIN FUNCTIONS WITH EVER GREATER ACCURACY

Identify the neurone assemblies and the mental processes brought into play in language, memory, calculation, preparing to act, learning to read, and even in consciousness itself.


Brain imaging supports the hypothesis that words can be detected subliminally. By combining functional MRI and electroencephalography, it can be shown that a subset of regions involved

in the reading process is also activated unconsciously when words are displayed imperceptibly.
Compare brains and map the objects that shape the cortex.

MEASURE INFORMATION PROCESSING STEPS

Determine the steps and brain regions activated when information is being processed. Visualise the bundles of connections through which this activation is transmitted between the different regions of the brain.





3D depiction from MRI images of the motor cortex, central structures and the connections linking them.
Connections leading to the left occipito-temporal region involved in reading (green, MRI).



UNRAVEL THE NEURAL CODE

What principle, what organisation, what relation between genes and brain specialisation?
Understand how the brain develops.
As there is a genetic code underlying cell function, what is the neural code governing brain function?

UNDERSTAND AND TREAT BRAIN DISORDERS

Psychiatric (schizophrenia), neurological (multiple sclerosis), neurodegenerative or developmental (dyslexia, dyscalculia).
Schizophrenia: impaired regions in a response test for a short-term memory task.




As there is a genetic code
underlying cell function,
what is the neural code
governing brain function?