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Actualité scientifique



Un acide aminé essentiel pour la tubuline et les microtubules
Caudron F, Denarier E, Thibout-Quintana JC. Brocard J, Andrieux A and Fourest-Lieuvin A
Mutation of Ser172 in yeast ß tubulin induces defects in microtubule dynamics and cell division.
PLoS One, 2010, 5: e13553

Une polyglutamylation de la tubuline équilibrée pour la survie neuronale
Rogowski K, van Dijk J, Magiera MM, Bosc C, Deloulme JC, Bosson A, Peris L, Gold ND, Lacroix B, Grau MB, Bec N, Larroque C, Desagher S, Holzer M, Andrieux A, Moutin MJ and Janke C
A family of protein deglutamylating enzymes associated with neurodegeneration.
Cell, 2010, 143(4): 564-578

Microtubules, souris et psychiatrie

La tyrosination de la tubuline est nécessaire pour l'interaction des microtubules et des protéines CAP-Gly
Peris L, Thery M, Faure J, Saoudi Y, Lafanechere L, Chilton JK, Gordon-Weeks P, Galjart N, Bornens M, Wordeman L, Wehland J, Andrieux A and Job D
Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.
Journal of Cell Biology, 2006, 174(6): 839-849

Un stabilisateur des microtubules, l'épothilone D a des propriétés anti-psychotropes
Baratier J, Peris L, Brocard J, Gory-Faure S, Dufour F, Bosc C, Fourest-Lieuvin A, Blanchoin L, Salin P, Job D and Andrieux A
Microtubule stabilizer ameliorates synaptic function and behavior in a mouse model for schizophrenia.
Biological Psychiatry, 2006, 60(11): 1224-1230

Les nouveaux amis de la protéine STOP : l'actine et le Golgi
Baratier J, Peris L, Brocard J, Gory-Faure S, Dufour F, Bosc C, Fourest-Lieuvin A, Blanchoin L, Salin P, Job D and Andrieux A
Phosphorylation of microtubule-associated protein STOP by calmodulin kinase II.
Journal of Biological Chemistry, 2006, 281(28):19561-19569
Gory-Faure S, Windscheid V, Bosc C, Peris L, Proietto D, Franck R, Denarier E, Job D and Andrieux A
STOP-like protein 21 is a novel member of the STOP family, revealing a Golgi localization of STOP proteins.
Journal of Biological Chemistry, 2006, 281(38):28387-28396

Phosphorylation de la tubuline ß par Cdk1 pendant la mitose
Fourest-Lieuvin A, Peris L, Gache V, Garcia-Saez I, Juillan-Binard C, Lantez V and Job D
Microtubule regulation in mitosis: Tubulin phosphorylation by the cyclin-dependent kinase Cdk1.
Molecular Biology of the Cell, 2006, 17: 1041-1050