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Presentation


Research in progress at the iMETI is focused on identifying what makes emergent diseases different, on the lessons to be learned from pathophysiological studies on these diseases in terms of understanding new biological functions, and on building new therapeutic strategies.

The iMETI’s work on new therapies involves research into the therapeutic use of somatic stem cells and genetic modifications in these cells.

The research carried out at the Institute of Emerging Diseases and Innovative Therapy is targeted on two disease models – HIV/Emerging Viruses, and Prions.   Work is now being oriented towards developing new vaccine-based therapies for HIV infection and studying the recently-discovered links between and prion diseases and Alzheimer’s disease.

 The creation of this Institute is a logical move forward from the HIV and prion research conducted at the CEA’s Fontenay-aux-Roses centre. Genetic and cell therapy has been added as a logical progression of the Fontenay-aux-Roses site’s expertise in HIV-derived vectors for preclinical studies, which is a key step as a prerequisite to the use of gene therapy protocols in clinical practice.
 The iMETI employs 44 permanent research staff in its three core departments: HIV/Emerging viruses and Immunotherapy, Prion diseases and Neurogeneration, and Innovative Therapies.