Monday March 16 2009
CEA
_____
To know more, « Utilisation du 129Xe hyperpolarisé pour une imagerie IRM plus sensible et sélective » sur les pages de l'iBiTec-S.
Bioprobes for more sensitive and more selective MRI
CEA
A team at iBiTec-S (CEA/Saclay) has now perfected a method for the simultaneous detection of biological events by nuclear magnetic resonance imaging (MRI).
These researchers have designed bioprobes based on xenon encapsulated in cage-like molecules of the cryptophane type. This encapsulation of xenon makes it possible to differentiate the specific signals obtained with each cage. In this study, they showed that it was possible simultaneously to use two different cages, dissolved in two non-miscible liquids, and obtained, in a few seconds, images of the xenon encapsulated in each of them in the course of a single experiment. This approach, which presents a very high detection sensitivity, opens up numerous perspectives for use in medical imaging to detect specific receptors or oxidative stress mediators. This research is of great interest for medical diagnostics and follow-up.
_____
To know more, « Utilisation du 129Xe hyperpolarisé pour une imagerie IRM plus sensible et sélective » sur les pages de l'iBiTec-S.