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Scientific services


Investigators offer some of their specific know-how to partners in the scope of research collaboration or fee-for-services projects. Here is a short list of services available.

MOLECULAR BIOLOGY and BIOCHEMISTRY

Gene cloning and expression of recombinant proteins, targeted mutagenesis:

NB: this service belongs to the Structural Biology Platform of the iBS

BIOCHEMISTRY

Proteomics services :

  • this platform offers several services for the analysis of protein samples and is open to CEA and non CEA labs.

NB: this service belongs to the Institute of Cellular and Molecular radiation biology (iRCM)

Protein quality control using the Termal Shift Assay method:

  • Fluorescence-based thermal shift assays are a general method for identifying ligands, target proteins, and for screening protein stability in different buffer conditions. To know more about TSA...

NB: this service belongs to the Structural Biology Platform of the iBS.

CELLULAR BIOLOGY

  • Flow cytometry and cell sorting platform :

The Cytometry and Cell Sorting facility at the Institute of Cellular and Molecular Radiation Biology (CEA) provides instrumentation and technical expertise (3 experts), for the development of collaborative projects involving flow cytometric analysis and cell sorting.

Download the platform sheet here.

NB: this service belongs to the Institute of Cellular and Molecular radiation biology (iRCM)

IN VIVO IMAGING

Isotopic labeling, radiopharmaceutical production and validation for bio-medical imaging (contact: frederic.dolle@cea.fr) :

Molecular labeling and radiopharmaceutic production for SPECT imaging (with the following Tc99m, I123 et TI201 radionuclids).

Molecular labeling and new radiotracers (F18, FDG) for TEP imaging.

NB: these services are part of the Bio-medical imaging platform of the SHJF.

NANOTECHNOLOGY

Carbon nanotubes C13 and C14labeling:

Download the platform sheet here.

Nanoparticles functionalization.

Download the platform sheet here.

NB: these services are part of the expertise of the Department of the Molecular Labeling and Bio-organic Chemistry lab (SCBM) homed at the Institute of Biology and Technology of Saclay (iBiTec-s) .

PURIFICATION AND PRODUCTS CHARACTERIZATION

Purification and analysis of labeled compounds and radioactive wastes (HPLC, MS...).

Download the platform sheet here.

NB: these services are part of the expertise of the Department of the Molecular Labeling and Bio-organic Chemistry lab (SCBM) homed at the Institute of Biology and Technology of Saclay (iBiTec-s) .

CHEMICAL SYNTHESIS

Synthesis of ligands for actinides, catalysis, organocatalysis...

Natural compounds and bioactive analogs synthesis:

NB: these services are part of the expertise of the Department of the Molecular Labeling and Bio-organic Chemistry lab (SCBM) homed at the Institute of Biology and Technology of Saclay (iBiTec-s) .

SCREENING OF SPECIFIC MOLECULES

Screening for uranophil ligands by the SCP (sulfochlorophenol) method, contact frederic.taran@cea.fr
Screening of catalysts librairies by sandwich immunoassays, contact frederic.taran@cea.fr
Screening for molecules having an impact on iodide transport, contact yves.ambroise@cea.fr

NB: these services are part of the expertise of the Department of the Molecular Labeling and Bio-organic Chemistry lab (SCBM) homed at the Institute of Biology and Technology of Saclay (iBiTec-s) .

For any questions, please contact us: tto.life@cea.fr