CEA Direction des sciences du vivant : Biochips at the CEA

Biochips at the CEA

What is a BioChip ?
Symbiosis between Biology and Micro-Electronics has created the BioChip family: a field of microsystems dedicated to revolutionary biological analyses with high throughput performances.
On a few cm² of glass or silicon, biochips can manipulate and analyze thousands of different DNA sequences, as many proteins or even individualized living cells.

Various types of BioChips

DNA chips are functionalized with thousands of specific genetic sequences. They are used to analyze gene mutations and gene expression in response to a number of stimuli (environment, drugs, stress, cancer, development…). On a single chip, all human genes can be analyzed in a single experiment.



		Partner: Apibio
The reference: DNA chips on glass aim at the global genome analysis (typical density: 12 000 genes per cm²)

The Point-of-Care chip:
integration of DNA sample amplification and analysis by hybridization.

LabOnChips are miniaturized laboratories automating complex sample preparation and high throughput analysis.

Partner:

Cell-On-Chips are microsystems integrating live cells and offer researchers revolutionary ways to monitor and manipulate individually thousands of cells.

Partners:

The MeDICS chip for Individualized Cell Sorting and Analysis.

Scope
- Fundamental research
- Pharmaceutical and medical research
- Diagnostics & Therapeutics
- Biotechnology
- Health, Environment and Food Control.

Some partners of the CEA
Industrials: BioMérieux, Protéus, STMicroelectronics, Silicon Biosystems, Sanofi-SynthéLabo, ApiBio, Genset, Yamataké, NeuroTech.
Academia: INSERM, CNRS, INRA, ANRS (AIDS Research), AFM (French muscular dystrophy association), Université Libre de Bruxelles, Università di Bologna.

Contacts:
Life Sciences Division: C Vincent (christian.vincent@cea.fr)
Leti: P Puget