The PhD projects for 2012
The 31 PhD projects of the 2012 PhD Program are classified by Institute of the DSV.
| Institute of Biology and Technologies, Saclay research center | |
|---|---|
| Neurovascular pharmacology group
Leader : Aloïse Mabondzo
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| Subject : | Prediction of cerebral drug concentrations.
PhD supervisor : Henri BENECH
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| Institute of Biology and Technologies, Saclay research center | |
|---|---|
| Laboratory of structural biology and radiobiology (LBSR)
Leader : Sophie ZINN-JUSTIN
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| Subject : | Study of structural determinants associated to formation and resolution of human telomeres t-loop.
PhD supervisor : Marie-Héléne LEDU
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| Institute of Biology and Technologies, Saclay research center | |
|---|---|
| Tritium labelling, self-assembly group
Leader : Bernard ROUSSEAU
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| Subject : | Determination of the active conformation of Taxol using solid state NMR of tritiated analogues.
PhD supervisor : Bernard ROUSSEAU
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| Institute of Biology and Technologies, Saclay research center | |
|---|---|
| Epigenetic regulation and cancer group
Leader : Matthieu GERARD
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| Subject : | Identification of the transcriptional regulatory networks controlled by chromatin remodelling factors during embryonic stem cell differentiation.
PhD supervisor : Matthieu GERARD
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| Institute of Biology and Technologies, Saclay research center | |
|---|---|
| Oxidatives stresses & cancer group
Leader : Michel TOLEDANO
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| Subject : | Redox control of secretion and its alteration age-related diseases.
PhD supervisor : Michel TOLEDANO
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| Institute of Biology and Technologies, Saclay research center | |
|---|---|
| Enzymology and non ribosomal peptide biosynthesis group
Leader : Muriel GONDRY
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| Subject : | Cyclodipeptide synthases, a new family of enzymes for the biosynthesis of new bioactive molecules.
PhD supervisor : Muriel GONDRY
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| Institute of Biology and Technologies, Saclay research center | |
|---|---|
| Group function of zinc metalloproteases
Leader : Vincent DIVE
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| Subject : | Design of therapeutic compounds: Combination of multidisciplinary approaches to get deeper insight into intermolecular interactions.
PhD supervisor : Vincent DIVE
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| Genome Institute, Evry Research Center | |
|---|---|
| Laboratory of Bioinformatics sequence analysis (LABIS)
Leader : Patrick WINCKER
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| Subject : | Gene content of ecologically important species in marine plankton using metagenome sequence analysis.
PhD supervisor : Patrick WINCKER
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| Genome Institute, Evry Research Center | |
|---|---|
| Laboratory of Bioinformatic Analysis for Genomic and Metabolism (LABGEM)
Leader : Claudine MEDIGUE
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| Subject : | Exploration of the diversity of enzymatic protein families: towards the discovery of new enzymatic activities.
PhD supervisor : David VALLENET
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| Institute of Biomedical Imaging, Fontenay-aux-Roses research center | |
|---|---|
| Laboratory of Neurodegenerative Diseases (LMN)
Leader : Emmanuel Brouillet
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| Subject : | Cellular origins of metabolic deficits in Alzheimer's disease.
PhD supervisor : Gilles BONVENTO
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| Institute of Biomedical Imaging, Fontenay-aux-Roses research center | |
|---|---|
| Laboratory of Neurodegenerative Diseases (LMN)
Leader : Emmanuel BROUILLET
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| Subject : | Evaluation of the efficacy of new therapeutic approaches in mouse models of Alzheimer's disease based on quantitative methods of analysis of amyloid load.
PhD supervisor : Thierry DELZESCAUX
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| Institute of Biomedical Imaging, Orsay research center | |
|---|---|
| Laboratory of experimental molecular medicine
Leader : Anne FLÜRY-HERARD
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| Subject : | Molecular imaging & therapy of cancer by specific targeting of multimodal nanoparticles.
PhD supervisor : Frédéric DUCONGE
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| Institute of Biomedical Imaging, Saclay research center | |
|---|---|
| Laboratory of computer-assisted Neuroimaging (LNAO)
Leader : Jean-François MANGIN
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| Subject : | Compressed Sensing for parallel MRI at high magnetic field (7T).
PhD supervisor : Philippe CIUCIU
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| Institute of Emerging Diseases and Innovative Therapy, Fontenay-aux-Roses research center | |
|---|---|
| Laboratory of antiviral immunity (LIA)
Leader : Roger LE GRAND
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| Subject : | Exploring the mechanisms of natural control of HIV infection using non-human primate models.
PhD supervisor : Bruno VASLIN
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| Institute of Cellular and Molecular Radiation Biology, Caen research center | |
|---|---|
| Open laboratory for research with accelerated ions (LARIA)
Leader : Jean-Louis LEFAIX
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| Subject : | Radiosensitivity of human chondrocyte. Artificial cartilage's model for radiotherapy studies.
PhD supervisor : Yannick SAINTIGNY
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| Institute of Cellular and Molecular Radiation Biology, Evry research center | |
|---|---|
| Laboratory of Keratinocyte Genomics and Radiobiology (LGRK)
Leader : Michèle MARTIN
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| Subject : | Gorlin syndrome: Patched-1 gene and individual sensitivity to radiation.
Phd supervisor : Odile RIGAUD
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| Institute of Cellular and Molecular Radiation Biology, Fontenay-aux-Roses research center | |
|---|---|
| Laboratory for research in genetic instability (LRIG)
Leader : Pablo RADICELLA
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| Subject : | Role of the prion protein in the DNA damage response.
PhD supervisor : Anne BRAVARD
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| Institute of Cellular and Molecular Radiation Biology, Fontenay-aux-Roses research center | |
|---|---|
| Laboratory of nuclear dynamics and DNA repair (LNDR)
Leader : Karine DUBRANA
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| Subject : | Impact of nuclear organisation on DNA repair and génome stability.
PhD supervisor : Karine DUBRANA
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| Institute of Life Sciences Research and Technologies, Grenoble research center | |
|---|---|
| Group pathophysiology of the cytoskeleton
Leader : Annie ANDRIEUX
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| Subject : | MAP6, a microtubule associated protein : biochemical and stuctural properties.
PhD supervisor : Annie ANDRIEUX
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| Institute of Life Sciences Research and Technologies, Grenoble research center | |
|---|---|
| Bacterial pathogenesis and cellular responses group
Leader : Ina ATTREE
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| Subject : | Integrated approach of toxin injection by a bacterial pathogen: identification of novel anti-infectious targets.
PhD supervisor : Philippe HUBER
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| Institute of Life Sciences Research and Technologies, Grenoble research center | |
|---|---|
| Kinases in renal carcinoma group
Leader : Claude COCHET
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| Subject : | Protein kinases and renal carcinoma: prediction of synergistic effects of new drugs and optimization of their association for a better therapeutic action.
PhD supervisor : Odile FILHOL-COCHET
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| Institute of Life Sciences Research and Technologies, Grenoble research center | |
|---|---|
| Physics of cytoskeleton and morphogenesis group
Leader : Laurent BLANCHOIN
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| Subject : | In vitro reconstitution of biomimetic contractile systems.
PhD supervisor : Laurent BLANCHOIN
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| Institute of Life Sciences Research and Technologies, Grenoble research centere | |
|---|---|
| Biocatalysis group
Leader : Marc Fontecave
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| Subject : | Design of new electro- and photocatalysts for H2 production: toward the construction of a H2-evolving (photo)cathode by a molecular strategy
PhD supervisor : Murielle CHAVAROT-KERLIDOU
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| Institute of Life Sciences Research and Technologies, Grenoble research center | |
|---|---|
| Biomics laboratory
Leader : Xavier GIDROL
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| Subject : | Profiling Ub and Ubl pathways in prostate cancer (PRUB-in CaP).
PhD supervisor : Maxim BALAKIREV
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| Institute of Structural Biology, Grenoble research center | |
|---|---|
| Channels Group
Leader : Michel VIVAUDOU
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| Subject : | Structural and functional studies of the K-ATP channel and the mechanism of disease-causing mutations.
PhD supervisor : Michel VIVAUDOU
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| Institute of Structural Biology, Grenoble research center | |
|---|---|
| Biomolecular NMR Spectroscopy group
Leader : Bernhard BRUTSCHER
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| Subject : | Lpos, key protein regulators and potential new targets antibiotics.
PhD supervisor : Jean-Pierre SIMORRE
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| Institute of Structural Biology, Grenoble research center | |
|---|---|
| Dynamo group
Leader : Martin FIELD
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| Subject : | Molecular modeling studies of Coupled Electron Transfer Processes in Proteins.
PhD supervisor : Martin FIELD
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| Institute of Structural Biology, Grenoble research center | |
|---|---|
| Conserved ATPases/GTPases group
Leader : Jean-Michel JAULT
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| Subject : | Functionning mechanism of an ABC transporter from Streptococcus pneumoniae involved in the resistance towards antimicrobial peptides.
PhD supervisor : Jean-Michel JAULT
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| Institute of Environmental Biology and Biotechnology, Cadarache research center | |
|---|---|
| Laboratory of plant molecular ecophysiology (LEMP)
Leader : Michel HAVAUX
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| Subject : | Singlet oxygen signaling and photosynthetic acclimation of plants to environmental constraints.
PhD supervisor : Michel HAVAUX
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| Institute of Environmental Biology and Biotechnology, Marcoule research center | |
|---|---|
| Laboratory of target protein studies (LEPC)
Leader : Claude VIDAUD
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| Subject : | Analytical strategies based on ICP/MS and ESI/MS for the characterization of uranium biological targets.
PhD supervisor : Agnès HAGEGE
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| Institute of Environmental Biology and Biotechnology, Cadarache research center | |
|---|---|
| Laboratory of plant genetics and biophysic (LGBP)
Leader : Christophe ROBAGLIA
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| Subject : | Manipulating energy signaling to improve the transformation of sunlight into biofuel.
PhD supervisor : Benjamin FIELD
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